Cathepsin L Antibody

Synonimy: CTSL, CTSL1
Typ przeciwciała: Polyclonal
Pochodzenie: Rabbit
Izotyp: Rabbit IgG
Klon:
Reaktywność: Human
Immunogen: Recombinant human Cathepsin L protein (Cat # 1135)
NCBI: P07711
Gene ID: 1514
Stężenie: 0.5 mg/ml
100 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
Przeznaczenie: Western blot
Western blot: 1-4 µg/ml.
For Research Use Only! Not to be used in humans.
Informacje: Cathepsin L, a lysosomal endopeptidase expressed in most eukaryotic cells, is a member of the papain-like family of cysteine proteinases.1-3 Cathepsin L plays a major role in antigen processing, tumor invasion and metastasis, bone resorption, and turnover of intracellular and secreted proteins involved in growth regulation.4-6 Although commonly recognized as a lysosomal protease, cathepsin L is also secreted. This broad-spectrum protease is potent in degrading several extracellular proteins (laminins, fibronectin, collagens I and IV, elastin, and other structural proteins of basement membranes) as well as serum proteins and cytoplasmic and nuclear proteins.
Temp. przechowywania: -20 °C
Czas przydatności: 12 months