GHBP Antibody

Synonimy: GHR, GHBP, GH receptor, Growth hormone binding protein, Somatotropin receptor
Typ przeciwciała: Polyclonal
Pochodzenie: Rabbit
Izotyp: Rabbit IgG
Klon:
Reaktywność: Human
Immunogen: Recombinant human GHBP (Cat # 4972)
NCBI: P10912
Gene ID: 2690
Stężenie: 0.5 mg/ml
100 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
Przeznaczenie: Western blot
Western blot: 1-4 µg/ml.
For Research Use Only! Not to be used in humans.
Informacje: GHBP is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Human Recombinant GHBP expressed from E. coli is a single, non-glycosylated, polypeptide chain containing 237 amino acids and having a molecular mass of 30.3 kDa.
Temp. przechowywania: -20 °C
Czas przydatności: 12 months