Glutamine Synthetase, human recombinant

GLNS, GS, PIG43, PIG59, GLUL

NCBI ID genu: 2752
NCBI Symbol genu: GLUL
Pochodzenie genu: Human
Źródło: E. coli
Czystość: > 85% SDS-PAGE, N/A N/A
Aktywność biologiczna: Specific activity is > 2.000 pmol/min/ug, and is defined as the amount of enzyme that convert L-glutamate to L-glutamine per miunte at pH 7.5 at 37C in coupled system with PK/LDH.
Stężenie: 1 mg/ml
Forma: In 20 mM Tris-HCl buffer (pH8.0) containing 10% glycerol 1 mM DTT, 0.1 mM PMSF

GLUL also known as Glutamine synthetase. It is a trimetallic enzyme containing two divalent cation sites and one monovalent cation site per subunit. GLUL is able to regulate intracellular concentrations of glutamate and catalyzes the synthesis of glutamine form glutamate and ammonia. It is ubiquitously expressed in the human and plays a major role for many metabolic pathways such as cell proliferation, inhibition of apoptosis, and cell signaling. Recombinant Human GLUL was expressed in E.coli and purified by using conventional chromatography techniques.

Temp. przechowywania: -20°C
Czas przechowywania: 12 months