F7 | Coagulation factor VII antibody

Immunogen: Purified full length recombinant protein P08709
Źródło: hen
Klonalność: polyclonal
Reaktywność: human
Przewidywana reaktywność: primates
Czystość: total IgY at 11 mg/ml in 0.9% NaCl, 0.1% sodium azide
Postać: liquid
Aplikacje: Western blot (WB)
Zalecane rozcieńczenie: 1: 5 000 - 1: 10 000 with standard ECL (WB), 1: 1000 - 1: 5 000 (ELISA)
Nr UniProt: P08709
Nr TAIR:
Przechowywanie: store at 4°C; make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
Uwagi: he IgY fraction is isolated by a two-step PEG precipitation procedure followed by ammonium sulphate precipitation
Powiązane produkty: AS00 001 | anti-Coagulation factor VIIa IMS01-015-308 | anti-Coagulation factor VIII AS05 058 | anti-Coagulation factor IXIMS01-137-306 | anti-Coagulation factor XII
Dodatkowe informacje: the antibody, in dilution 1: 10 000, will detect 1 ng of factor VII in immunoblotting

Factor VII is a 52 kDa multi-domain, single chain plasma glycoprotein synthesised in the liver and having abnormal circulating concentration of between 400 and 600 g/L. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa through cleavage by thrombin, Factor Xa, Factor IXa or Factor XIIa. Factor VIIa converts Factor X to Factor Xa, which in turn converts prothrombin to thrombin.
Literatura: to be added when available